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staphylococcal scalded skin syndrome
Staphylococcal scalded skin syndrome, (SSSS), also known as Pemphigus neonatorum or Ritter's disease, or Localized bullous impetigo is a dermatological condition caused by ''Staphylococcus aureus''.
==Pathophysiology==
The syndrome is induced by epidermolytic exotoxins (exfoliatin) A and B, which are released by ''S. aureus'' and cause detachment within the epidermal layer; by breaking down the desmosomes. One of the exotoxins is encoded on the bacterial chromosome, while the other is encoded on a plasmid. These exotoxins are proteases that cleave desmoglein-1, which normally holds the granulosum and spinosum layers together.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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